{"id":1047,"date":"2018-03-21T09:40:43","date_gmt":"2018-03-21T07:40:43","guid":{"rendered":"http:\/\/medicann.sk\/?p=1047"},"modified":"2018-03-21T09:40:43","modified_gmt":"2018-03-21T07:40:43","slug":"co-je-thca","status":"publish","type":"post","link":"http:\/\/medicann.sk\/co-je-thca\/","title":{"rendered":"\u010co je THCA ?"},"content":{"rendered":"<p>Konope, ako rastlina bolo dlh\u00fa dobu prehliadan\u00e9 najm\u00e4 kv\u00f4li psychoakt\u00edvnym \u00fa\u010dinkom najzn\u00e1mej\u0161ieho kanabinoidu zvan\u00e9ho <a href=\"http:\/\/medicann.sk\/thc-a-cbd-zakladne-rozdiely\/\">THC<\/a>. Podobn\u00fd kanabinoid naz\u00fdvan\u00fd THCA (kyselina tetrahydrokanabinolov\u00e1) pon\u00faka nov\u00fd poh\u013ead a\u00a0nov\u00e9 rie\u0161enia.<\/p>\n<p>\u0160irok\u00e1 \u0161k\u00e1la kanabinoidov pr\u00edtomn\u00fdch v konope a in\u00fdch fytochemik\u00e1li\u00ed ako s\u00fa terp\u00e9ny, preuk\u00e1zali r\u00f4zne mo\u017en\u00e9 terapeutick\u00e9 vyu\u017eitie bez toho, aby sp\u00f4sobili stavy opojenia (zh\u00falenos\u0165). K\u00fdm kanabidiol (<a href=\"http:\/\/medicann.sk\/co-je-cbd-ako-ucinkuje-vsetko-co-vas-zaujima-o-liecivom-kanabidiole\/\">CBD<\/a>) je sp\u00e1jan\u00fd s najv\u00e4\u010d\u0161\u00edm po\u010dtom farmakologick\u00fdch \u00fa\u010dinkov, kanabinoid, ktor\u00fd zamedz\u00ed tomu, \u017ee pacient dosiahne hladinu opojenia, je kyselina tetrahydrokanabinolov\u00e1 alebo THCA.<\/p>\n<p><strong><u>Molekul\u00e1rna \u0161trukt\u00fara THCA<\/u><\/strong><\/p>\n<p>Ako nazna\u010duje n\u00e1zov, THCA \u00fazko s\u00favis\u00ed s THC, tak\u017ee by sa musel prid\u00e1va\u0165 do extraktov z konope, ktor\u00e9 poch\u00e1dzaj\u00fa z odr\u00f4d, ktor\u00e9 obsahuj\u00fa THC. Je prekurzorom THC, \u010do znamen\u00e1, \u017ee je to jedna chemick\u00e1 reakcia. T\u00e1to reakcia sa zvy\u0161uje pri su\u0161en\u00ed a intenz\u00edvnom ohreve, ako je varenie alebo faj\u010denie, tak\u017ee sa vyskytuje iba v \u010derstvom, nesu\u0161enom konope a konopn\u00e9 extrakty s\u00a0pridan\u00fdm THCA by sa mali udr\u017eiava\u0165 v\u00a0chlade. To tie\u017e znamen\u00e1, \u017ee THCA m\u00e1 sporn\u00e9 pr\u00e1vne postavenie a nemus\u00ed by\u0165 mo\u017en\u00e9 leg\u00e1lne ho pred\u00e1va\u0165 tam, kde je konope resp. kanabinoidy nez\u00e1konn\u00e9. Premena THCA na THC vo vn\u00fatri tela je v\u0161ak ve\u013emi obmedzen\u00e1. Navy\u0161e niektor\u00e9 kanabinoidy a terp\u00e9ny p\u00f4sobia proti opojn\u00fdm \u00fa\u010dinkom THC, tak\u017ee prid\u00e1vanie THCA do dobre vyv\u00e1\u017een\u00e9ho konopn\u00e9ho extraktu m\u00f4\u017ee vyvola\u0165 mierne zn\u00ed\u017een\u00fa psychoaktivitu.<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.midwestcompassion.org\/wp-content\/uploads\/2016\/07\/decarb1.jpg?w=1170&#038;ssl=1\" alt=\"S\u00favisiaci obr\u00e1zok\" data-recalc-dims=\"1\" \/><\/p>\n<p><strong><u>THCA nie je opojn\u00e9, ale \u010do teda rob\u00ed ? \u00a0<\/u><\/strong><\/p>\n<p>\u00da\u010dinky proti nevo\u013enosti<\/p>\n<p>Jedno z\u00a0mo\u017en\u00fdch vyu\u017eit\u00ed THCA je ako l\u00e1tka na podporu chuti do jedla resp. ako l\u00e1tka proti zvracaniu. \u00a0V \u0161t\u00fadii na potkanoch, THCA v\u00fdznamne zn\u00ed\u017eila spr\u00e1vanie a zvracanie vyvolan\u00e9 nauzeou, \u010diasto\u010dne kv\u00f4li \u00fa\u010dinku na kanabinoidn\u00e9 receptory CB1. Tento \u00fa\u010dinok bol v\u00e4\u010d\u0161\u00ed ako pri THC. Autori tie\u017e spomenuli \u00fa\u010dinnos\u0165 THC proti nevo\u013enosti u pacientov s n\u00e1dorov\u00fdm ochoren\u00edm. \u010eal\u0161ie lie\u010debn\u00e9 vyu\u017eitie THCA namiesto THC m\u00f4\u017ee by\u0165 najm\u00e4 z\u00a0d\u00f4vodu nedostatku psychoakt\u00edvnych \u00fa\u010dinkov THCA.<\/p>\n<p>Protiz\u00e1palov\u00e9 \u00fa\u010dinky<\/p>\n<p>THCA m\u00f4\u017ee tie\u017e pom\u00f4c\u0165 protiz\u00e1palov\u00fdm \u00fa\u010dinkom in\u00fdch kanabinoidov. V\u00fdskum zistil, \u017ee zatia\u013e \u010do THC a CBD neinhibuj\u00fa z\u00e1palov\u00e9 cyklooxygen\u00e1zov\u00e9 (COX) enz\u00fdmy, THCA je schopn\u00e1 inhibova\u0165 COX1 o viac ako 50% a COX2 o viac ako 30%. \u00dalohou enz\u00fdmov COX1 a COX2 je podpori\u0165 produkciu z\u00e1palov\u00fdch l\u00e1tok zn\u00e1mych ako prostagland\u00edny z omega-6 mastn\u00fdch kysel\u00edn. Takto tie\u017e funguje be\u017en\u00fd aspir\u00edn proti bolesti a\u00a0preto u\u017e\u00edvanie omega-3 mastn\u00fdch kysel\u00edn, ako s\u00fa napr\u00edklad rybie oleje, m\u00f4\u017ee zmierni\u0165 z\u00e1pal a v\u00fdsledn\u00fa boles\u0165, preto\u017ee omega-3 &#8222;vylu\u010duj\u00fa&#8220; omega-6. Av\u0161ak COX1 a COX2 m\u00f4\u017eu by\u0165 potrebn\u00e9 pri <a href=\"http:\/\/medicann.sk\/konope-ako-ulava-pri-orto-ochoreniach\/\">lie\u010dbe zlomen\u00edn kost\u00ed<\/a>, tak\u017ee v tejto situ\u00e1cii by bolo najlep\u0161ie vyhn\u00fa\u0165 sa THCA v prospech CBD, ktor\u00e9 je protiz\u00e1palov\u00e9 pomocou in\u00fdch mechanizmov a dokonca CBD dok\u00e1\u017ee ur\u00fdchli\u0165 proces hojenia kost\u00ed.<\/p>\n<p>Okrem t\u00fdchto pr\u00ednosov m\u00f4\u017ee THCA tie\u017e ma\u0165 ochrann\u00e9 \u00fa\u010dinky na mozgov\u00e9 bunky. V \u010fal\u0161ej laborat\u00f3rnej \u0161t\u00fadii sa zistilo, \u017ee m\u00e1 antioxida\u010dn\u00e9 schopnosti, ke\u010f s\u00fa my\u0161ie mozgov\u00e9 bunky vystaven\u00e9 neurotox\u00ednu a maj\u00fa ist\u00fd ochrann\u00fd \u00fa\u010dinok proti bunkovej smrti.<\/p>\n<p>Celkovo mo\u017eno poveda\u0165, \u017ee THCA m\u00f4\u017ee by\u0165 \u010fal\u0161\u00edm s\u013eubn\u00fdm kanabinoidom, je v\u0161ak potrebn\u00fd \u010fal\u0161\u00ed v\u00fdskum na \u013eu\u010foch.<\/p>\n<p>Viac info o mo\u017enostiach konopnej lie\u010dby vo svete v\u00e1m poskytneme aj na email: pacient@medicann.sk<\/p>\n<h6><\/h6>\n<h6>Zdroj:\u00a0https:\/\/herb.co\/2017\/05\/11\/thca\/<\/h6>\n<h6>Autorsk\u00e9 pr\u00e1va MediCann Slovakia a uveden\u00e9 zdroje. V\u0161etky pr\u00e1va vyhraden\u00e9.<br \/>\nfyzick\u00e9 osoby ZDIE\u013dA\u0164 m\u00f4\u017eu bez potreby \u017eiada\u0165 povolenie. FB str\u00e1nky a ine m\u00e9di\u00e1 (tla\u010den\u00e9, elektronick\u00e9) nemaj\u00fa pr\u00e1vo toto zdie\u013ea\u0165 bez uvedenia zdroja alebo po\u017eiadania o zdie\u013eanie!<br \/>\nza pochopenie \u010fakujem-e V\u00e1\u0161 MediCann<\/h6>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Konope, ako rastlina bolo dlh\u00fa dobu prehliadan\u00e9 najm\u00e4 kv\u00f4li psychoakt\u00edvnym \u00fa\u010dinkom najzn\u00e1mej\u0161ieho kanabinoidu zvan\u00e9ho THC. Podobn\u00fd kanabinoid naz\u00fdvan\u00fd THCA (kyselina tetrahydrokanabinolov\u00e1) pon\u00faka nov\u00fd poh\u013ead a\u00a0nov\u00e9 rie\u0161enia. \u0160irok\u00e1 \u0161k\u00e1la kanabinoidov pr\u00edtomn\u00fdch [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[10],"tags":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/medicann.sk\/wp-content\/uploads\/2018\/03\/2016-06-21.jpg?fit=960%2C720","_links":{"self":[{"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/posts\/1047"}],"collection":[{"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/comments?post=1047"}],"version-history":[{"count":0,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/posts\/1047\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/media\/1048"}],"wp:attachment":[{"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/media?parent=1047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/categories?post=1047"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/medicann.sk\/wp-json\/wp\/v2\/tags?post=1047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}